Inflammatory bowel disease: An Indian perspective Jain M, Venkataraman J Published Apr 2021, in the Indian Journal of medical research. Abstract Inflammatory bowel disease (IBD) in recent times is causing a significant healthcare burden as both ulcerative colitis and Crohn's disease (CD) require lifelong therapy and constant monitoring. The current review highlights the concerns in a country like India with special reference to the changing trends of IBD, risk attribution and

Serial measurements of faecal calprotectin may discriminate intestinal tuberculosis and Crohn's disease in patients started on antitubercular therapy Sharma V, Verma S, Kumar-M P, Mandavdhare HS, Singh H, Shah J, Kalsi D, Dutta A, Mishra S, Prasad KK, Sharma AK, Dutta U Published Mar 2021, in the European journal of gastroenterology & hepatology. Abstract Aim: We aimed to ascertain the efficacy and feasibility of exclusive enteral nutrition (EEN) as an induction and re-induct

Trends of inflammatory bowel disease at a tertiary care center in northern India Sood A, Kaur K, Singh A, Midha V, Mahajan R, Bansal N, Mehta V, Singh D Published Jul 2021, in the Intestinal research. Abstract Background/aims: Inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn's disease (CD), is increasingly being reported from India and other Asian countries. This study looks into the changing trends of IBD at a tertiary care center in north India

Small intestinal bacterial overgrowth in patients with inflammatory bowel disease: A case-control study Ghoshal UC, Yadav A, Fatima B, Agrahari AP, Misra A Published Aug 2021, in the Indian Journal of Gastroenterology. Abstract Background: Though small intestinal bacterial overgrowth (SIBO) is known in inflammatory bowel disease (IBD), the data on it are scanty and have limitations. Methods: Data on IBD patients undergoing glucose hydrogen breath test (GHBT) were retrospectiv

TPMT and NUDT15 polymorphisms in thiopurine induced leucopenia in inflammatory bowel disease: a prospective study from India Grover N, Bhatia P, Kumar A, Singh M, Lad D, Mandavdhare HS, Samanta J, Prasad KK, Dutta U, Sharma V Published Aug 2021, in the BMC Gastroenterology. Abstract Background: Polymorphisms in thiopurine methyltransferase (TPMT) and Nudix hydrolase-15 (NUDT15) have been implicated as the predominant cause of thiopurine induced leukopenia in the Western count

Cytomegalovirus enterocolitis with subsequent diagnosis of coexisting new-onset inflammatory bowel disease Luangsirithanya P, Treewaree S, Pongpaibul A, Pausawasdi N, Limsrivilai J Published Feb 2021, in the medicine (Baltimore) Abstract Introduction: Gastrointestinal (GI) cytomegalovirus (CMV) infection coexisting with or followed by a diagnosis of inflammatory bowel disease (IBD) is infrequently reported. Not recognizing this condition may delay IBD diagnosis in patients wi

Long-term effects of increasing omega-3, omega-6 and total polyunsaturated fats on inflammatory bowel disease and markers of inflammation: a systematic review and meta-analysis of randomized controlled trials Ajabnoor SM, Thorpe G, Abdelhamid A, Hooper L Published Aug 2021, in the European journal of nutrition. Abstract Background and aim: Effects of long-chain omega-3 (LCn3) and omega-6 fatty acids on prevention and treatment of inflammatory bowel diseases (IBD, including Cr

Extraintestinal Manifestations of Inflammatory Bowel Disease: Current Concepts, Treatment, and Implications for Disease Management Rogler G, Singh A, Kavanaugh A, Rubin DT Published Aug 2021, in the Gastroenterology. Abstract Inflammatory bowel diseases (IBDs) are systemic diseases that manifest not only in the gut and gastrointestinal tract, but also in the extraintestinal organs in many patients. The quality of life for patients with IBD can be substantially affected by the

Comorbidity before and after a diagnosis of inflammatory bowel disease Bernstein CN, Nugent Z, Shaffer S, Singh H, Marrie RA Published Sep 2021, in the Alimentary pharmacology & therapeutics Abstract Background: Comorbidity is an important predictor of how disease course in inflammatory bowel (IBD) evolves. Aims: To determine pre-diagnosis relative rates (RR) and post-diagnosis hazard ratios (HR) of component diseases of the Charlson Comorbidity Index (CCI) in a cohort study

The role of precision nutrition in the modulation of microbial composition and function in people with inflammatory bowel disease Sasson AN, Ingram RJM, Zhang Z, Taylor LM, Ananthakrishnan AN, Kaplan GG, Ng SC, Ghosh S, Raman M Published Sep 2021, in the lancet. Gastroenterology & hepatology. Abstract Inflammatory bowel diseases, principally Crohn's disease and ulcerative colitis, are multifactorial chronic conditions. Alterations in gut microbial patterns partly affect disea

Antibodies Against Glycoprotein 2 Are Specific Biomarkers for Pediatric Crohn's Disease Shpoliansky M, Roggenbuck D, Pinsker M, Salamon N, Weiss B, Shouval DS, Werner L Published Aug 2021, in the Digestive diseases and sciences. Abstract Background: Serological markers can assist in accurate differentiation between Crohn's disease (CD) and ulcerative colitis (UC). One such marker is anti-glycoprotein 2 (anti-GP2) which was shown to be a specific marker for CD in adult patient

Impaired Quality of Working Life in Inflammatory Bowel Disease Patients van Gennep S, de Boer NKH, Gielen ME, Rietdijk ST, Gecse KB, Ponsioen CY, Duijvestein M, D'Haens GR, Löwenberg M, de Boer AGEM Published Sep 2021, in the Digestive diseases and sciences Abstract Background: Work-related aspects are important determinants of health for inflammatory bowel disease (IBD) patients. Aims: We aimed to describe quality of working life (QWL) in IBD patients and to assess variables