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Key articles from high impact journals in last month
April 2022
A novel unconventional T cell population enriched in Crohn’s disease.
Elisa Rosati, Gabriela Rios Martini, Mikhail V Pogorelyy, Anastasia A Minervina, Frauke Degenhardt, Mareike Wendorff, Soner Sari, Gabriele Mayr, Antonella Fazio, Christel Marie Dowds, Charlotte Hauser, Florian Tran, Witigo von Schönfels, Julius Pochhammer, Maria A Salnikova, Charlot Jaeckel, Johannes Boy Gigla, Sanaz Sedghpour Sabet, Matthias Hübenthal , Esther Schiminsky, Stefan Schreiber, Philip C Rosenstiel , Alexander Scheffold, Paul G Thomas, Wolfgang Lieb, Bernd Bokemeyer, Maria Witte, Konrad Aden, Alexander Hendricks, Clemens Schafmayer, Jan-Hendrick Egberts, Ilgar Z Mamedov, Petra Bacher, Andre Franke
Published in Gastroenterology, March 2022.
Efficacy and Safety of Tofacitinib in Ulcerative Colitis Based on Prior Tumor Necrosis Factor Inhibitor Failure Status
William J Sandborn, Laurent Peyrin-Biroulet, Ala I Sharara, Chinyu Su, Irene Modesto, Rajiv Mundayat, L Mert Gunay, Leonardo Salese, Bruce E Sands
Published in Clinical Gastroenterology and Hepatology, March 2022.
Favourable tolerability and drug survival of tioguanine versus methotrexate after failure of conventional thiopurines in Crohn’s disease
E H J Savelkoul, M H J Maas, A R Bourgonje, F Crouwel, V B C Biemans, N den Broeder, M G V M Russel, T E H Römkens, N K de Boer, G Dijkstra, F Hoentjen
Published in: Journal of Crohn's and Colitis, March 2022.
Antibody decay, T cell immunity and breakthrough infections following two SARS-CoV-2 vaccine doses in inflammatory bowel disease patients treated with infliximab and vedolizumab
Simeng Lin, Nicholas A Kennedy, Aamir Saifuddin, Diana Muñoz Sandoval, Catherine J Reynolds, Rocio Castro Seoane, Sherine H Kottoor, Franziska P Pieper, Kai-Min Lin, David K Butler, Neil Chanchlani, Rachel Nice, Desmond Chee, Claire Bewshea, Malik Janjua, Timothy J McDonald, Shaji Sebastian, James L Alexander, Laura Constable, James C Lee, Charles D Murray, Ailsa L Hart, Peter M Irving, Gareth-Rhys Jones, Klaartje B Kok, Christopher A Lamb, Charlie W Lees, Daniel M Altmann, Rosemary J Boyton, James R Goodhand, Nick Powell, Tariq Ahmad, CLARITY IBD study
Published in Nature Publications, March 2022
Decreased serum iron concentration and total iron binding capacity are associated with serious Crohn’s disease
Jingling Su, Yandan Ren, Lupeng Liu, Yiqun Hu, Huaxiu Shi, Jianlin Ren, Chenxi Xie
Published in Scientific Reports, March 2022
Polypharmacy in Patients with Inflammatory Bowel Disease: Prevalence and Outcomes in a Single-center Series
Francisco Mesonero, Cristina Fernández, Eugenia Sánchez-Rodríguez, Ana García-García Paredes, Carla Senosiain, Agustín Albillos, Antonio López-Sanromán
Published in Journal of clinical gastroenterology, March 2022
Bile Acids: Key Players in Inflammatory Bowel Diseases?
Aicha Kriaa, Vincent Mariaule, Amin Jablaoui, Soufien Rhimi, Hela Mkaouar, Juan Hernandez, Brice Korkmaz, Adam Lesner, Emmanuelle Maguin, Ali Aghdassi, Moez Rhimi
Published in Cells, March 2022
Prognostic Value of Colonic Tissue and Blood Eosinophils in Ulcerative Colitis
Maria L Haasnoot, Aart Mookhoek, Marjolijn Duijvestein, Geert R A M D'Haens, Albert J Bredenoord
Published in Inflammatory bowel diseases, March 2022