April - 2022

Apr 29, 2022

Use of biologics and small molecule drugs for the management of moderate to severe UC

Use of biologics and small molecule drugs for the management of moderate to severe ulcerative colitis: IG-IBD technical review based on the GRADE methodology Stefanos Bonovas, Claudia Pansieri, Daniele Piovani, Fabio Salvatore Macaluso, Ambrogio Orlando, Stefano Festa, Claudio Papi, Daniela Pugliese, Alessandro Armuzzi Published Feb 2022, in Digestive and liver disease: official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of th

IBDENC ENC

Apr 29, 2022

Polypharmacy in Patients with Inflammatory Bowel Disease: Prevalence and Outcomes

Polypharmacy in Patients with Inflammatory Bowel Disease: Prevalence and Outcomes in a Single-center Series Francisco Mesonero, Cristina Fernández, Eugenia Sánchez-Rodríguez, Ana García-García Paredes, Carla Senosiain, Agustín Albillos, Antonio López-Sanromán Published in: Journal of clinical gastroenterology, March 2022. Abstract Background: Polypharmacy can complicate the course and management of chronic diseases, and has been little explored in patients with inflammatory

IBDENC ENC

Apr 22, 2022

Decreased serum iron concentration and total iron binding capacity are associated

Decreased serum iron concentration and total iron binding capacity are associated with serious Crohn’s disease Jingling Su, Yandan Ren, Lupeng Liu, Yiqun Hu, Huaxiu Shi, Jianlin Ren, Chenxi Xie Published in: Scientific reports, March 2022. Abstract This study aimed to investigate whether serum indicators related to iron stores in the body are associated with clinical and endoscopic disease severity. Eighty-four patients with Crohn’s disease (CD) and twenty-four healthy volunt

IBDENC ENC

Apr 22, 2022

Prognostic Value of Colonic Tissue and Blood Eosinophils in Ulcerative Colitishttps://academic.o

Prognostic Value of Colonic Tissue and Blood Eosinophils in Ulcerative Colitis Maria L Haasnoot, Aart Mookhoek, Marjolijn Duijvestein, Geert R A M D'Haens, Albert J Bredenoord Published in: Inflammatory bowel diseases, March 2022. Abstract Background It has been suggested that eosinophils may be a prognostic marker of disease outcome in ulcerative colitis (UC), but conflicting data exist. The objective was to investigate the extent of mucosal eosinophils and peripheral blood

IBDENC ENC

Apr 22, 2022

Efficacy and Safety of Tofacitinib in Ulcerative Colitis Based on Prior Tumor Necrosis Factor Inhibi

Efficacy and Safety of Tofacitinib in Ulcerative Colitis Based on Prior Tumor Necrosis Factor Inhibitor Failure Status William J Sandborn, Laurent Peyrin-Biroulet, Ala I Sharara, Chinyu Su, Irene Modesto, Rajiv Mundayat, L Mert Gunay, Leonardo Salese, Bruce E Sands Published in: Clinical Gastroenterology and Hepatology, March 2022. Background & Aims Tofacitinib is an oral, small-molecule Janus kinase inhibitor for the treatment of ulcerative colitis (UC). We summarize the eff

IBDENC ENC

Apr 22, 2022

Bile Acids: Key Players in Inflammatory Bowel Diseases? https://www.mdpi.com/2073-4409/11/5/901/

Bile Acids: Key Players in Inflammatory Bowel Diseases? Aicha Kriaa, Vincent Mariaule, Amin Jablaoui, Soufien Rhimi, Hela Mkaouar, Juan Hernandez, Brice Korkmaz, Adam Lesner, Emmanuelle Maguin, Ali Aghdassi, Moez Rhimi Published in: Cells, March 2022. Abstract Inflammatory bowel diseases (IBDs) have emerged as a public health problem worldwide with a limited number of efficient therapeutic options despite advances in medical therapy. Although changes in the gut microbiota com

IBDENC ENC

Apr 22, 2022

Low-dose azathioprine and allopurinol versus azathioprine monotherapy in patients with UC

Low-dose azathioprine and allopurinol versus azathioprine monotherapy in patients with ulcerative colitis (AAUC): An investigator-initiated, open, multicenter, parallel-arm, randomised controlled trial Marianne Kiszka-Kanowitz, Klaus Theede, Sandra Bohn Thomsen, Jacob Tveiten Bjerrum, Jørn Brynskov, Ida Benedikte Gottschalck, Elena Akimenko, Karen Lisa Hilsted, Anders Neumann, Signe Wildt, Lone Larsen, Jens Kristian Munk, Per Holger Ibsen, Huma Gul Rehana Janjua, Lise Lotte G

IBDENC ENC

Apr 21, 2022

Favourable tolerability and drug survival of tioguanine versus methotrexate after failure of convent

Favourable tolerability and drug survival of tioguanine versus methotrexate after failure of conventional thiopurines in Crohn’s disease E H J Savelkoul, M H J Maas, A R Bourgonje, F Crouwel, V B C Biemans, N den Broeder, M G V M Russel, T E H Römkens, N K de Boer, G Dijkstra, F Hoentjen Published in: Journal of Crohn's and Colitis, March 2022. Abstract Background and Aims Both methotrexate and tioguanine can be considered as treatment options in patients with Crohn’s disease

IBDENC ENC

Apr 21, 2022

Antibody decay, T cell immunity and breakthrough infections following two SARS-CoV-2 vaccine dose

Antibody decay, T cell immunity and breakthrough infections following two SARS-CoV-2 vaccine doses in inflammatory bowel disease patients treated with infliximab and vedolizumab Simeng Lin, Nicholas A Kennedy, Aamir Saifuddin, Diana Muñoz Sandoval, Catherine J Reynolds, Rocio Castro Seoane, Sherine H Kottoor, Franziska P Pieper, Kai-Min Lin, David K Butler, Neil Chanchlani, Rachel Nice, Desmond Chee, Claire Bewshea, Malik Janjua, Timothy J McDonald, Shaji Sebastian, James L A

IBDENC ENC

Apr 14, 2022

A novel unconventional T cell population enriched in Crohn’s disease.

A novel unconventional T cell population enriched in Crohn’s disease. Elisa Rosati, Gabriela Rios Martini, Mikhail V Pogorelyy, Anastasia A Minervina, Frauke Degenhardt, Mareike Wendorff, Soner Sari, Gabriele Mayr, Antonella Fazio, Christel Marie Dowds, Charlotte Hauser, Florian Tran, Witigo von Schönfels, Julius Pochhammer, Maria A Salnikova, Charlot Jaeckel, Johannes Boy Gigla, Sanaz Sedghpour Sabet, Matthias Hübenthal , Esther Schiminsky, Stefan Schreiber, Philip C Rosenst

IBDENC ENC

Apr 13, 2022

Safety and efficacy of non-fluoroscopic endoscopic dilatation of gastrointestinal tuberculosis relat

Safety and efficacy of non-fluoroscopic endoscopic dilatation of gastrointestinal tuberculosis related strictures Pankaj Kumar, Anuraag Jena, Chhagan Lal Birda, Harjeet Singh, Pankaj Gupta, Kaushal Kishor Prasad, Usha Dutta & Vishal Sharma Published Feb 2022, in the BMC gastroenterology. Abstract Introduction Stricturing gastrointestinal tuberculosis (GITB) may result in persistent symptoms even after antitubercular therapy (ATT) and may require surgical intervention. Data on

IBDENC ENC

Apr 7, 2022

Emerging IBD demographics, phenotype and treatment in South Asia, South-East Asia and Middle East

Emerging IBD demographics, phenotype and treatment in South Asia, South-East Asia and Middle East: Preliminary findings from the IBD-Emerging Nations' Consortium Rupa Banerjee, Partha Pal , Ida Hilmi, Uday C Ghoshal, Devendra C Desai, M Masudur Rahman, Usha Dutta, Syed A Mohiuddin, Munnera Al Mohannadi, Mathew Philip, Ganesh N Ramesh, Madunil A Niriella, Arjuna P De Silva, H Janaka de Silva, Pises Pisespongsa , Julajak Limsrivilai , Satimai Aniwan, Metthananda Nawarathne , Ni

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