March - 2022

Mar 24, 2022

Prevalence of extra intestinal manifestations in ulcerative colitis and associated risk factors

Prevalence of extra intestinal manifestations in ulcerative colitis and associated risk factors Krishn Kant Rawal, Varun P. Shukla, Shabbir Chikani, Milan Thakkar, Mukesh Ruparelia & Rajesh K. Chudasama Published Sep 2021, in the Springer Link. Abstract Background The data on prevalence of extraintestinal manifestations (EIM) in ulcerative colitis (UC) are scanty and highly variable. Methods Consecutive patients with UC were prospectively evaluated from November 2016 to Augu

IBDENC ENC

Mar 24, 2022

Cytomegalovirus in ulcerative colitis: an evidence-based approach to diagnosis and treatment

Cytomegalovirus in ulcerative colitis: an evidence-based approach to diagnosis and treatment Anuraag Jena, Shubhra Mishra, Anupam Kumar Singh, Aravind Sekar &Vishal Sharma Published Feb Oct 2021, in the Expert Rev Gastroenterol Hepatol. ABSTRACT Introduction The detection of cytomegalovirus (CMV) in the setting of inflammatory bowel disease often creates confusion whether CMV is a ‘bystander’ or ‘disease.’ Areas Covered This review discusses the clinical conundrum of CMV in u

IBDENC ENC

Mar 18, 2022

A Notch/STAT3-driven Blimp-1/c-Maf-dependent molecular switch induces IL-10 expression in human CD4+

A Notch/STAT3-driven Blimp-1/c-Maf-dependent molecular switch induces IL-10 expression in human CD4+ T cells and is defective in Crohn´s disease patients Jonas Ahlers, Andrej Mantei, Laura Lozza, Manuela Stäber, Frederik Heinrich, Petra Bacher, Thordis Hohnstein, Lutz Menzel, Simge G Yüz, Daniel Alvarez-Simon, Anne Rieke Bickenbach, Carl Weidinger, Nadine Mockel-Tenbrinck, Anja A Kühl, Britta Siegmund, Jochen Maul, Christian Neumann, Alexander Scheffold Published Feb 2022, in

IBDENC ENC

Mar 17, 2022

Safety and efficacy of non-fluoroscopic endoscopic dilatation of gastrointestinal tuberculosis

Safety and efficacy of non-fluoroscopic endoscopic dilatation of gastrointestinal tuberculosis related strictures Pankaj Kumar, Anuraag Jena, Chhagan Lal Birda, Harjeet Singh, Pankaj Gupta, Kaushal Kishor Prasad, Usha Dutta & Vishal Sharma Published Feb 2022, in the BMC gastroenterology. Abstract Introduction Stricturing gastrointestinal tuberculosis (GITB) may result in persistent symptoms even after antitubercular therapy (ATT) and may require surgical intervention. Data on

IBDENC ENC

Mar 17, 2022

Effectiveness and Durability of COVID-19 Vaccination in 9447 Patients with IBD

Effectiveness and Durability of COVID-19 Vaccination in 9447 Patients with IBD: A Systematic Review and Meta-Analysis Anuraag Jena 1, Deepak James 1, Anupam K Singh 1, Usha Dutta 1, Shaji Sebastian 2, Vishal Sharma Published Feb 2022, in the Clinical gastroenterology and Hepatology. Background And Aims The serological responses after severe acute respiratory syndrome coronavirus 2 vaccination may be attenuated in immunocompromised individuals. The study aimed to systematicall

IBDENC ENC

Mar 16, 2022

High prevalence of mental health illness in IBD patients with high caregiver burden

High prevalence of mental health illness in IBD patients with high caregiver burden in the developing world: An analysis of risk factors from the IBD Emerging Nations Consortium (IBD-ENC) R Banerjee, P Pal, I Hilmi, M Rahman, T T Aye, N Joshi, U Ghoshal, P Alavinejad, K Peddi, S Mudigonda Inflammatory Bowel Disease Emerging nations Consortium (IBD ENC) Published Jan 2022, in the Journal of CROHN’s and COLITIS Abstract Background Mental health is an important yet most neglecte

IBDENC ENC

Mar 16, 2022

COVID-19 vaccine-induced antibody responses in immunosuppressed patients with IBD

COVID-19 vaccine-induced antibody responses in immunosuppressed patients with inflammatory bowel disease (VIP): a multicentre, prospective, case-control study James L Alexander, Nicholas A Kennedy, Hajir Ibraheim, Sulak Anandabaskaran, Aamir Saifuddin, Rocio Castro Seoane, Zhigang Liu, Rachel Nice, Claire Bewshea, Andrea D'Mello, Laura Constable, Gareth R Jones, Sharmili Balarajah, Francesca Fiorentino, Shaji Sebastian, Peter M Irving, Lucy C Hicks, Horace R T Williams, Alexa

IBDENC ENC

Mar 12, 2022

Markers of systemic inflammation in acute attacks of ulcerative colitis

Markers of systemic inflammation in acute attacks of ulcerative colitis: What level of C-reactive protein constitutes severe colitis Anthony Croft, Anton Lord, Graham Radford-Smith Published Feb 2022, in the Journal of CROHN’s and COLITIS. Abstract Background and Aims The erythrocyte sedimentation rate [ESR] as a component of the Truelove and Witts Criteria [TWC] is the traditional inflammatory marker used for the assessment of ulcerative colitis [UC] activity. However, the C

IBDENC ENC

Mar 11, 2022

Exclusive enteral nutrition with oral polymeric diet helps in inducing clinical and biochemical

Exclusive enteral nutrition with oral polymeric diet helps in inducing clinical and biochemical remission in adults with active Crohn's disease Pradeep Kakkadasam Ramaswamy DNB Published Oct 2021, in the Journal of Parenteral and Enteral Nutrition Hepatology. Abstract Background and Aims Exclusive enteral nutrition (EEN) is not routinely used as induction therapy for adults with active Crohn's disease (CD). The aim of this study was to assess the effectiveness of EEN with ora

IBDENC ENC

Mar 10, 2022

Emerging IBD demographics, phenotype and treatment in South Asia, South-East Asia and Middle East: P

Emerging IBD demographics, phenotype and treatment in South Asia, South-East Asia and Middle East: Preliminary findings from the IBD-Emerging Nations' Consortium Rupa Banerjee 1, Partha Pal 1, Ida Hilmi 2, Uday C Ghoshal 3, Devendra C Desai 4, M Masudur Rahman 5, Usha Dutta 6, Syed A Mohiuddin 7, Munnera Al Mohannadi 7, Mathew Philip 8, Ganesh N Ramesh 9, Madunil A Niriella 10, Arjuna P De Silva 10, H Janaka de Silva 10, Pises Pisespongsa 11, Julajak Limsrivilai 12, Satimai A

IBDENC ENC

Mar 8, 2022

Identification of gene expression profiles associated with an increased risk of post-operative recur

Identification of gene expression profiles associated with an increased risk of post-operative recurrence in Crohn’s disease Marjolaine Ngollo, Kevin Perez, Nassim Hammoudi, Yuri Gorelik, Marc Delord, Claire Auzolle, Hugo Bottois, Dominique Cazals-Hatem, Madeleine Bezault, Stéphane Nancey, Benjamin Pariente, Xavier Treton, Mathurin Fumery, Anthony Buisson, Nicolas Barnich, Philippe Seksik, REMIND study group investigators; Shai S Shen-Orr, Lionel Le Bourhis, Matthieu Allez Pu

IBDENC ENC

Mar 5, 2022

Viral enteric infections in acute severe ulcerative colitis

Viral enteric infections in acute severe ulcerative colitis Szymon Ostrowski, Anthony Croft Published Feb 2022, in the Journal of CROHN’s and COLITIS Abstract Background and Aims Excluding superimposed enteric infection is critical in the management of acute severe ulcerative colitis [ASUC]. Whilst infection with Clostridium difficile and cytomegalovirus have been shown to increase colectomy and mortality rates, no data exist regarding the impact of common viral enteropathoge

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